Parkinsons malady (PD) is an get along related neurodegenerative disorder that affects ones ability to realise their muscles, which in turn influence movement and balance. Prior to being formally recognized by James Parkinson in 1817, it is unexplored specifically how long PD has been around (Esselink, 2006). Statistically, Parkinsons is a progressive disorder that affects roughly 0.3% of the general population. The onset of PD usually occurs between the ages of 60 and 70, however there argon some cases that occurs before the age of 40 (Esselink, 2006). This disease is shortly incurable, however it is not fatal. Symptoms of Parkinsons disease mostly overwhelm motor impairments, such as tremors at rest, inflexibility, bradykinesia, turbulence in gait and balance issues (Esselink, 2006, Antonini, 2010, Lau, 2011, Aarsland, 2011). Other symptoms include loss of facial nerve expressions, dementia, and other psychological illnesses.
Scientists still do not tell apart what motilitys the development of PD, but most believe that it is a kind of genetic factors and exposure to certain environmental factors. Currently, most cases of this disease has been deemed sporadic occurrences, scientists have made a small baring that mutation of gene is the culprit to the rise of PD.
(Selkoe, 2004) Individuals first alter with this disease soon realize the symptoms progressively gets worse as the loss of the dopaminergic neurons causes the uncontrollable spasms. As the loss increases, the worse the spasms capture because the neurotransmitter dopamine is responsible for controlling and regulating movement. (Breen, 2011) Although most of the symptoms of PD affect the muscular system, the disease itself originates in the nervous system. The devil most popular treatments today are levodopa and deep humor stimulation. More research and clinical trials must be do in order to success fully diagnose the exact cause of this degenerative disease.
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